^ Blum K, Werner T, Carnes S, Carnes P, Bowirrat A, Giordano J, Oscar-Berman M, Gold M (2012). "Sex, drugs, and rock 'n' roll: hypothesizing common mesolimbic activation as a function of reward gene polymorphisms". Journal of Psychoactive Drugs. 44 (1): 38–55. doi:10.1080/02791072.2012.662112. PMC 4040958. PMID 22641964. It has been found that deltaFosB gene in the NAc is critical for reinforcing effects of sexual reward. Pitchers and colleagues (2010) reported that sexual experience was shown to cause DeltaFosB accumulation in several limbic brain regions including the NAc, medial pre-frontal cortex, VTA, caudate, and putamen, but not the medial preoptic nucleus. Next, the induction of c-Fos, a downstream (repressed) target of DeltaFosB, was measured in sexually experienced and naive animals. The number of mating-induced c-Fos-IR cells was significantly decreased in sexually experienced animals compared to sexually naive controls. Finally, DeltaFosB levels and its activity in the NAc were manipulated using viral-mediated gene transfer to study its potential role in mediating sexual experience and experience-induced facilitation of sexual performance. Animals with DeltaFosB overexpression displayed enhanced facilitation of sexual performance with sexual experience relative to controls. In contrast, the expression of DeltaJunD, a dominant-negative binding partner of DeltaFosB, attenuated sexual experience-induced facilitation of sexual performance, and stunted long-term maintenance of facilitation compared to DeltaFosB overexpressing group. Together, these findings support a critical role for DeltaFosB expression in the NAc in the reinforcing effects of sexual behavior and sexual experience-induced facilitation of sexual performance. ... both drug addiction and sexual addiction represent pathological forms of neuroplasticity along with the emergence of aberrant behaviors involving a cascade of neurochemical changes mainly in the brain's rewarding circuitry.
Drug detox: Detox, short for detoxification, is the first phase in many substance abuse treatment programs. During detox, patients are monitored by professionals during their withdrawal from drugs. Medications, nutritional supplementation and fluid replacement may be provided to relieve withdrawal symptoms. At the same time, counseling is provided to encourage the patient to move forward to the next phase of rehabilitation.
The one that’s right for you depends on your situation and your goals. Many people find that a combination of treatments works best, and you can get them together through a program. Some of these are inpatient or residential programs, where you stay at a treatment center for a while. Others are outpatient programs, where you live at home and go to the center for treatment.
For example: As a result of heavy traffic, a recovering alcoholic may decide one afternoon to exit the highway and travel on side roads. This will result in the creation of a high-risk situation when he realizes he is inadvertently driving by his old favorite bar. If this individual is able to employ successful coping strategies, such as distracting himself from his cravings by turning on his favorite music, then he will avoid the relapse risk (PATH 1) and heighten his efficacy for future abstinence. If, however, he lacks coping mechanisms—for instance, he may begin ruminating on his cravings (PATH 2)—then his efficacy for abstinence will decrease, his expectations of positive outcomes will increase, and he may experience a lapse—an isolated return to substance intoxication. So doing results in what Marlatt refers to as the Abstinence Violation Effect, characterized by guilt for having gotten intoxicated and low efficacy for future abstinence in similar tempting situations. This is a dangerous pathway, Marlatt proposes, to full-blown relapse.

There is a strong correlation between alcohol abuse and violent crimes like assault, armed robbery, rape, and homicide. The U.S. Department of Justice reports that in up to half of all murders, the perpetrator consumed alcohol before committing the crime. Approximately 33 percent of sexual assault victims state that their assailant was under the influence of alcohol. In violent crimes where alcohol is involved, up to 60 percent of victims are injured or killed.
When you have a child struggling with substance abuse, attempting to handle it on your own can be extremely overwhelming and can eventually become your first and only priority. It may also be difficult to take the first step because addressing the problem is disruptive of school and extracurricular activities.2 However, addiction is far more disruptive to your child's life in the end, and treatment can work. Taking the time now to get help can save your child's life.
Engaging with Searidge's extensive aftercare program works efficiently with your daily responsibilities and individual and therapeutic needs and offers proven and crucial support for maintaining sobriety. Our Aftercare program offers group therapy sessions over the phone from the comfort and convenience of your own home. No need to sacrifice an entire evening driving to some location when you can pick up the phone and be connected to a welcoming group therapy session of 5 to 6 others talking with a counsellor, all of whom you may already know through your time at Searidge. You can also get individual counselling over the phone, or communicate with our Aftercare community through our private in-house social network site. Our Twitter and message services send out inspirational funny and engaging tweets and messages several times a day to our Aftercare community. We also offer refresher weekend getaways to alumni who want to reconnect more intensively. We also run a Smart Recovery Aftercare program and are part of the Smart Recovery community that offers virtual Internet meetings across Canada, the USA, England, and Australia. The wide array of Aftercare services including more intensive Sober living facilities are reviewed with each resident as part of their "Exit Plan" which assures them of our ongoing support as they return to successfully stand up to the challenges of their daily lives.
The United States' approach to substance abuse has shifted over the last decade, and is continuing to change. The federal government was minimally involved in the 19th century. The federal government transitioned from using taxation of drugs in the early 20th century to criminalizing drug abuse with legislations and agencies like the Federal Bureau of Narcotics (FBN) mid-20th century in response to the nation's growing substance abuse issue.[47] These strict punishments for drug offenses shined light on the fact that drug abuse was a multi-faceted problem. The President's Advisory Commission on Narcotics and Drug Abuse of 1963 addressed the need for a medical solution to drug abuse. However, drug abuse continued to be enforced by the federal government through agencies such as the DEA and further legislations such as The Controlled Substances Act (CSA), the Comprehensive Crime Control Act of 1984, and Anti-Drug Abuse Acts.
Once you determined whether or not your loved one requires an inpatient drug treatment program and decided how long he or she should stay, what else should you look for in an effective drug rehab program? There are a number of characteristics that signify a positive, safe, and efficient environment for your loved one that will promote growth and healing physically, mentally and emotionally. The Cycle Of Addiction - Unf*ck Yourself From The Modern World (E442)

Alcohol is also linked to self-harm, psychosis, and suicide and because it can impair judgement and lead to reckless, compulsive behaviour, many people who take their own lives do so while under the influence of alcohol. In fact, NHS Scotland has said that over half of all hospital admissions related to deliberate self-harm have a direct link to alcohol either immediately before or during the act.
"The most robust finding in the study is that those receiving any medication did much better than those who received no pills at all," says Professor Barbara Mason, Scripps Research Institute, and an author of the study. "This should be a wake-up call. With less than one percent of those seeking help for alcohol dependence receiving a prescription, medication is underutilized. Medication for alcoholism can offer patients an advantage for their recovery, especially in a real-world setting."
There are many places to turn for help. Not everybody requires medically supervised detox or an extended stint in rehab. The care you need depends on a variety of factors, including your age, drug-use history, medical or psychiatric conditions. In addition to doctors and psychologists, many clergy members, social workers, and counselors offer addiction treatment services.
Depressants, also known as CNS depressants, slow down brain activity to put the body in a state of extreme relaxation. Misuse occurs when people take high doses to achieve euphoria or use the drugs with alcohol or other drugs to enhance their effects. Sexual predators also use depressants such as GHB and Rohypnol to take advantage of their victims.

Medical detox in an addiction treatment center takes place in a fully-staffed medical facility where patients are monitored around the clock, and treatment for the side effects of withdrawal is provided as needed. Medications to reduce the intensity of withdrawal symptoms may be administered, and patients will not be released from detox until they are symptom-free and physically and mentally well enough to handle the daily routine of an addiction treatment regimen. Best Detox Program

Certain drugs (like cocaine, heroin, and methamphetamines) are infamous for how they can mess up the brain. Most people know to beware of their potency and danger. Other substances (such as alcohol, marijuana and painkillers) tend to be viewed quite differently. For many Americans, they are deemed to be much less dangerous. But is this view accurate?

Research shows drug use is more common among arrestees than the general population. The Office of National Drug Control Policy reported that 63 to 83 percent of people arrested in five major metropolitan areas in 2013 tested positive for at least one illicit drug. The three most common drugs present during tests were marijuana, cocaine and opiates, and many people tested positive for multiple drugs.
Psychological dependency is addressed in many drug rehabilitation programs by attempting to teach the patient new methods of interacting in a drug-free environment. In particular, patients are generally encouraged, or possibly even required, to not associate with peers who still use the addictive substance. Twelve-step programs encourage addicts not only to stop using alcohol or other drugs, but to examine and change habits related to their addictions. Many programs emphasize that recovery is a permanent process without culmination. For legal drugs such as alcohol, complete abstention—rather than attempts at moderation, which may lead to relapse—is also emphasized ("One is too many, and a thousand is never enough.") Whether moderation is achievable by those with a history of abuse remains a controversial point, but is generally considered unsustainable.[2]
^ "Diagnostic and Statistical Manual of Mental Disorders: DSM-5 (5th edition)2014 102 Diagnostic and Statistical Manual of Mental Disorders: DSM-5 (5th edition) Washington, DC American Psychiatric Association 2013 xliv+947 pp. 9780890425541(hbck);9780890425558(pbck) £175 $199 (hbck); £45 $69 (pbck)". Reference Reviews. 28 (3): 36–37. 2014-03-11. doi:10.1108/rr-10-2013-0256. ISSN 0950-4125.

3. The meat of the program (psychotherapy and behavioral treatments) – This is one of the most important phases of rehabilitation, as it begins to give you a base for future sobriety. During this phase, you work with an alcohol counselor to address your current mental and emotional condition and understand where it’s coming from.  Then, you can start to make behavioral and attitudinal changes to remain sober, prevent relapse, and start living a happy life. If you are dedicated – the chances for your alcohol rehab program to work are increases and you have made significant steps towards becoming sober long-term. Best Drug Rehabilitation Programs Backed By Research. Find Out Why.
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