Today, more than 7 million people suffer from an illicit drug disorder, and one in four deaths results from illicit drug use. In fact, more deaths, illnesses and disabilities are associated with drug abuse than any other preventable health condition. People suffering from drug and alcohol addiction also have a higher risk of unintentional injuries, accidents and domestic violence incidents.
It is important to understand that without timely, expert support for your drug addiction, your symptoms can become progressively worse over time, and you may find that you need to consume more and more of the substance in question in order to experience the desired effects. Continued drug use can have an extremely negative effect on all areas of your life including your hobbies, social life, work performance, ability to function on a day-to-day basis, your relationships with family and friends, and your general physical and psychological wellbeing. Untreated drug addiction may also lead to the development of alcohol addiction and other behavioural addictions, causing a whole host of additional problems.
Once a person is addicted to alcohol, to stop it may take hospitalizations, rehabilitations, and re-rehabilitations all of which hemorrhage expenses — not to mention destroy relationships and property. The estimated cost to the system of this specialized addiction care is $24.6 billion. Since addiction is a disease that rewires the brain, the individual is unlikely to quit through “willpower” alone, and it often takes something dramatic (or “hitting rock bottom”) before they will make changes. There are costs associated with these dramatic scenarios. In the case of car accidents caused by driving drunk, costs include not just hospitalization, but the cost to insurance companies, car owners, municipal employees responding to the accident, and a continued chain reaction of costs that could ultimately include vehicular homicides and funeral expenses.
The path to drug addiction begins with the voluntary act of taking drugs. But over time, a person's ability to choose not to do so becomes compromised. Seeking and taking the drug becomes compulsive. This is mostly due to the effects of long-term drug exposure on brain function. Addiction affects parts of the brain involved in reward and motivation, learning and memory, and control over behavior.
Medical detox in an addiction treatment center takes place in a fully-staffed medical facility where patients are monitored around the clock, and treatment for the side effects of withdrawal is provided as needed. Medications to reduce the intensity of withdrawal symptoms may be administered, and patients will not be released from detox until they are symptom-free and physically and mentally well enough to handle the daily routine of an addiction treatment regimen.
As alcohol abuse progresses from dependency to addiction, your need for alcohol will become increasingly overwhelming. You may start to spend more and more of your time drinking or thinking about drinking, leaving little time for anyone or anything else. This can affect your ability to take care of responsibilities at home and work, and can have a negative impact on your relationships with family members, friends, and work colleagues. Addiction Recovery: 12 Steps and Beyond (TTA Podcast 321)
Gateway Foundation is a national provider that has 17 convenient drug treatment centers in Illinois, Delaware and California to serve our patients in the places and communities they call home. We put our patients at the center of their substance abuse treatment—life-saving treatment that stays with them throughout their lives. Through individualized treatment, we’re able to help them discover what will work best for them in their journey to overcome drug and alcohol addiction.
Upregulation of the cAMP signal transduction pathway in the locus coeruleus by CREB has been implicated as the mechanism responsible for certain aspects of opioid-induced physical dependence.[20] The temporal course of withdrawal correlates with LC firing, and administration of α2 agonists into the locus coeruleus leads to a decrease in LC firing and norepinephrine release during withdrawal. A possible mechanism involves upregulation of NMDA receptors, which is supported by the attenuation of withdraw by NMDA receptor antagonists.[21] Physical dependence on opioids has been observed to produce an elevation of extracellular glutamate, an increase in NMDA receptor subunits NR1 and NR2A, phosphorylated CaMKII, and c-fos. Expression of CaMKII and c-fos is attenuated by NMDA receptor antagonists, which is associated with blunted withdrawal in adult rats, but not neonatal rats[22] While acute administration of opioids decreases AMPA receptor expression and depresses both NMDA and non-NMDA excitatory postsynaptic potentials in the NAC, withdrawal involves a lowered threshold for LTP and an increase in spotaneous firing in the NAc.[23]
Inpatient or residential treatment  can also be very effective, especially for those with more severe problems (including co-occurring disorders). Licensed residential treatment facilities offer 24-hour structured and intensive care, including safe housing and medical attention. Residential treatment facilities may use a variety of therapeutic approaches, and they are generally aimed at helping the patient live a drug-free, crime-free lifestyle after treatment. Examples of residential treatment settings include:
At Passages Malibu, we believe your alcohol addiction is simply the symptom of an underlying condition which, when brought to light and resolved, will effectively end your cycle of chemical dependency. When you check into Passages Malibu, you will be assigned a 10-person team consisting of therapists and administrators. This team will work with you through the duration of your stay, evaluating and adjusting your program as you make progress. No two weeks will be alike. Instead, your program will be constantly evolving as you advance toward complete success. At our luxurious rehab center, we know that detox is an extremely important choice. In order to ensure your total safety, security, and comfort, we will provide you with a supervised detox. Our team of nurses is available 24/7 to provide you with the best clinical care.
As a dual diagnosis patient, you could expect to work with doctors and therapists who are experts in treating the conditions you suffer from. Your treatment may be very different from what others in your facility are receiving. Your stay at the residential facility might be longer as well. But rest assured that you will get the specialised treatment you need to deal with your dual diagnosis.
Inpatient residential rehab involves an extended time period for treatment, regardless of the substance. Programs typically last 30–45 days, or longer, depending on each client’s needs. Clients are required to stay at the facility for the entirety of the program, including overnight. Although there is no single treatment that’s right for everyone, inpatient rehab is one of the most effective forms of care for drug and alcohol addiction.

Nalmefene, an opiate antagonist that is similar in its chemical structure to naltrexone, is one of the most recent drugs being investigated for the treatment of alcoholism. Like naltrexone (sold as ReVia, Depade, or Vivitrol), nalmefene deprives the person struggling with substance use of the pleasurable feelings associated with drinking. But nalmefene is less toxic to the liver than naltrexone. As of 2013, nalmefene was still undergoing clinical trials through the U.S. National Institutes of Health before receiving FDA approval. From Rehab to a Body Bag | Dying for Treatment: VICE Reports (Full Length)
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